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The Lankenau Institute for Medical Research (LIMR) has its roots in biomedical investigations initiated in the late 1800s at The Lankenau Hospital, which at that time was called The German Hospital of Philadelphia and was located at Girard and Corinthian Avenues in the City. Using its medical connections in Germany, where so many medical and biochemical advances have occurred historically, the Hospital had many firsts in Philadelphia such as the first bacteriological and chemical laboratory and the first X-ray imaging device. During the past two decades there has been a great expansion of research at Lankenau into the genetics and cell biology of cancer, cardiovascular disease, aging, and transgenic mouse models of disease.